All About Binders

From: Quicksilver Scientific - Tuesday Feb 28,2023 10:15 pm

Dear Leslie,

Binding agents or ‘binders’ are a key component of Phase III detoxification. A binder is a substance that attaches to toxins in the gut, helping prevent them from being recirculated via enterohepatic circulation. Essentially, binders are like an additional “organ of detoxification,” facilitating the timely removal of toxins from the body. Binders support toxin removal by adsorbing toxins. Different from passive absorption, adsorption is the chemical process of attracting, binding, and accumulating particles on a surface. At an atomic level, adsorption involves the sharing of electrons between the surface of the “adsorbent,” such as activated charcoal, and the “adsorbate,” the substance being adsorbed. Therefore, ingesting binders allows toxins to be chemically “captured” in the gut and removed, rather than recirculated. BINDERS HELP PREVENT RECIRCULATION OF TOXINS Toxins that are transported from the liver to the intestine can be reabsorbed into systemic circulation through a process called enterohepatic circulation. Recirculating toxins wreak havoc on numerous body systems. For example, mycotoxins can cause cellular damage when recirculated between the intestine, bloodstream, and liver. Endotoxin, also known as lipopolysaccharide (LPS), can travel through enterohepatic circulation, triggering many serious and unwanted symptoms.1,2 Conversely, when a binder is present in the intestine, it can capture toxins, such as mycotoxins and LPS, helping to prevent their reabsorption.

3 BINDERS YOU SHOULD KNOW The natural world offers a variety of binding agents, including activated charcoal, chitosan, and bentonite clay. Activated charcoal contains millions of tiny pores that adsorb toxins in the gut, including metals, bacterial endotoxin, and mycotoxins.3,4 Hospitals and emergency rooms have long used activated charcoal to treat cases of poisoning in children and adults. Activated charcoal is often made from coconut shells or bamboo and is well-tolerated and readily excreted in the stool. Chitosan, another potent binding agent, is a water-soluble polysaccharide derived from the outer skeleton of shellfish. Despite being derived from shellfish, chitosan has not been found to trigger allergenicity in shellfish-allergic individuals because the allergenic proteins have been removed. Chitosan binds heavy metals and microbes and may also support the growth of beneficial gut bacteria, which play crucial roles in the immune system.5,6 Bentonite clay made from volcanic ash known as “Montmorillonite”, is a creamy grey color with a soft and fine consistency. Due to the small particle size, bentonite clay has a vast surface area capable of binding to multiple substances. In addition, clay has extraordinary adsorptive properties and is rich in minerals, including silica, magnesium, sodium, calcium, iron, and potassium.7 Clay is a broad-spectrum antimicrobial that helps bind LPS, mold, heavy metals, microbes, and various chemicals.8

THE BEST BINDER IS A BROAD-SPECTRUM BINDER There is no one binding agent that can eliminate all toxins. When detoxing, it is best to utilize a combination of binders to capture an array of toxins, as different natural binders have different affinities and capacities for toxin removal. Overall, binders are great multi-purpose health tools capable of adsorbing toxins in the gut and reducing the body's toxic burden. However, the benefits of binders don't stop with their adsorbent properties. Many natural binding agents also improve the health of the gut microenvironment, creating a waste elimination system that can more efficiently remove toxins.

REFERENCES 1. Mahaney WC et al. Mineral and chemical analyses of soils eaten by humans in Indonesia. Int J Environ Health Res. 2000; 10(2): 93-109. 2. Silberman J, Galuska MA, and Taylor A. Activated charcoal. Stat Pearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482294/ 3. WHO model list of essential medicines. World Health Organization. Updated September 2021. Accessed October 2022. https://www.who.int/groups/expert-committee-on-selection-and-use-of-essential-medicines/essential-medicines-lists. 4. Megarbane B et al. Management of pharmaceutical and recreational drug poisoning. Ann Intensive Care. 2020; 10: 157. 5. Pegues AS et al. The removal of 14C labeled endotoxin by activated charcoal. Int J Artif Organs. 2(3): 153-158. 6. AN Y et al. Performance evaluation of activated carbon with different pore sizes and functional groups for VOC adsorption by molecular simulation. Chemosphere. 2019; 227: 9-16. 7. Suthongsa S et al. Effects of dietary levels of chitooligosaccharides on ileal digestibility of nutrients, small intestinal morphology and crypt cell proliferation in weaned pigs. Livestock Sci. 2017; 198:37-44. 8. Neuvonen PJ and Olkkola KT. Oral activated charcoal in the trea6tment of intoxications: role of single and repeated doses. Med Toxicol. 1988; 3: 33-58

DETOX

IMMUNITY

LONGEVITY

CBD

Remember to sign in to your account to view and purchase CBD products. Don’t have an account?
Sign up here >>

*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

LONGEVITY SCIENCE

WHY QS

QS DELIVERY SYSTEMS

No longer want to receive these emails? .
Quicksilver Scientific 1960 Cherry St Louisville, CO 80027

More emails from Quicksilver Scientific

Feb 25,2023 04:03 pm - Saturday

ONE MORE WEEK! Join Dr. Shade in Santa Monica!

Feb 21,2023 09:15 pm - Tuesday

The Quicksilver Scientific Institute is LIVE!

Feb 20,2023 02:31 pm - Monday

March 4th - Join Dr. Shade in Santa Monica!

Feb 19,2023 04:02 pm - Sunday

Launching Tuesday! The Quicksilver Scientific Institute

Feb 18,2023 12:15 am - Saturday

Don't Miss This

Feb 16,2023 02:30 pm - Thursday

Launching Next Week: The Quicksilver Scientific Institute

Feb 15,2023 02:00 pm - Wednesday

TONIGHT! Join Dr. Shade for our February Virtual Webinar